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Medicine / health science fair project:
A reliable way to store and transport vaccines




Science Fair Project Information
Title: A reliable way to store and transport vaccines
Subject: Medicine / Health
Subcategory: Medical Instruments
Grade level: Middle School - Grades 7-9
Academic Level: Ordinary
Project Type: Building / Engineering
Cost: Medium
Awards: Google Science Fair Finalist
Affiliation: Google Science Fair
Year: 2015
Materials: Phase change material (PCM), double-acting pneumatic cylinder,
Techniques: Pressure-Enthalpy diagram,
Concepts: Vaccine refrigeration, vapor compression refrigeration, Cold chain system
Description: This project is about a “Cold chain system” that maintains vaccine temperature in the range of 2-8°C throughout the transport process: manufacturer to distributor, distributor to remote clinic, and clinic to patient.
Link: https://www.googlesciencefair.com/projects/en/2015/f60386
Short Background

Vaccine refrigerator

Vaccine refrigerators are designed to store vaccines and other medical products at a stable temperature to ensure they do not degrade. In developing countries with a sunny climate, solar-powered vaccine refrigerators are common.

Many vaccines must be stored at low temperatures, some below -15°C, and others between 2 and 8°C. If vaccines are not stored correctly they can lose their effectiveness.

According to the Center for Disease Control, failure to adhere to recommended specifications for storage and handling of immunobiologics can reduce or destroy their potency, resulting in inadequate or no immune response in the recipient. Maintenance of vaccine quality is the shared responsibility of all handlers of vaccines from the time a vaccine is manufactured until administration.

According to the Immunization Action Coalition, all vaccines should be stored in a refrigerator or freezer that is designed specifically for the storage of biologics or, alternatively, in a separate dedicated unit. A dorm-style combination refrigerator-freezer unit with just one exterior door has been shown to be unacceptable no matter where the vaccine was placed inside the unit. Stand-alone refrigerator or freezer units are best for storage needs. With retail pharmacies now playing a major role in pneumonia, influenza and shingles immunization programs, the value of critical vaccines being stored in pharmacy refrigerators has reached a new high. In fact, it is not uncommon for many pharmacies to now have over $100,000 of product in a single refrigerator during peak seasons.

It is estimated that $20 million is wasted annually from poor refrigeration, and up to 35% of vaccines are affected by improper storage. Accurate and uniform temperature in a refrigerator plays a key role in ensuring the life of vaccines, reagents and other biologicals. Research has shown that minor variances in temperature such as those in a household refrigerator can compromise the effectiveness of your biologicals, risking up to thousands of dollars in valuable contents.

These high values, coupled with today’s requirements and guidelines, make it essential to use proper refrigeration equipment designed for vaccine storage.

Solar powered vaccine refrigerators:

In developing countries the electricity grid often does not reach rural areas, and is not always reliable. As keeping vaccines at the appropriate temperature is vital, Solar powered refrigerators are a cost-effective alternative that can be highly reliable. A typical system will use a solar photovoltaic panel to generate electricity from sunlight, and a deep cycle battery to store energy for operation overnight, although newer fridges which have revolutionary Sure Chill Technology or Direct Drive technology do not need batteries to maintain temperatures for many days without sunlight.

The World Health Organisation maintains a list of products related to vaccines that it approves for use, including refrigerators.

See also:
https://en.wikipedia.org/wiki/Vaccine_refrigerator
https://en.wikipedia.org/wiki/Solar-powered_refrigerator

Source: Wikipedia (All text is available under the terms of the GNU Free Documentation License and Creative Commons Attribution-ShareAlike License.)

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